Pentoxifylline, a drug that makes the blood less "sticky," is used to increase blood circulation in conditions such as intermittent claudication (a possible complication of atherosclerosis in which impaired blood circulation causes severe pain in calf muscles during walking or exercising).
The herb garlic (Allium sativum) is taken to lower cholesterol, among many other proposed uses.
The herb ginkgo (Ginkgo biloba) has been used to treat Alzheimer's disease and ordinary age-related memory loss, among many other uses.
Because of these risks, you should not combine ginkgo and pentoxifylline without physician supervision.
The supplement policosanal is used to reduce cholesterol levels. It also intereferes with platelet clumping, creating a risk of interactions with blood-thinning drugs.
Based on these findings, you should not combine pentoxifylline and policosanol except under medical supervision.
The substance vinpocetine is sold as a dietary supplement for the treatment of age-related memory loss and impaired mental function.
The herb white willow (Salix alba) , also known as willow bark, is used to treat pain and fever. White willow contains a substance that is converted by the body into a salicylate similar to the blood-thinner aspirin. For this reason, white willow might add to the effects of pentoxifylline, possibly thinning the blood too much.
It may be advisable to avoid white willow while taking pentoxifylline except under medical supervision.
Herbs and supplements that impair the blood's ability to coagulate (clot) might add to the effects of pentoxifylline, possibly increasing the risk of excessive bleeding. This includes most prominently vitamin E .
Numerous other substances could conceivably present this risk, including mesoglycan , bromelain (from the fruit and stem of pineapple, Ananas comosus ), chamomile(Matricaria recutita) , Coleus forskohlii , danshen (Salvia miltorrhiza) , dong quai(Angelica sinensis) , feverfew(Tanacetum parthenium) , fish oil , ginger(Zingiber officinale) , horse chestnut(Aesculus hippocastanum) , OPCs (oligomeric proanthocyanidins), papaya (Carica papaya) , and red clover(Trifolium pratense) .
- Reviewer: EBSCO CAM Review Board
- Review Date: 09/2014 -
- Update Date: 09/18/2014 -