Protease inhibitors include amprenavir (Agenerase), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), and saquinavir (Fortovase, Invirase).
The bottom line: If you have HIV, don't take St. John's wort! Furthermore, if you have been stabilized on HIV medications while taking St. John's wort, if you stop taking the herb your blood levels of the drugs could rise, potentially leading to increased side effects.
Because this could increase the risk of drug side effects, if you take protease inhibitors, the safest approach is to avoid grapefruit juice altogether.
The herb garlic is widely used in the belief that it can help prevent heart disease. However, it may not be safe to combine garlic supplements with protease inhibitors.
- Reviewer: EBSCO CAM Review Board
- Review Date: 08/2013 -
- Update Date: 08/22/2013 -