Proposed Natural Treatments
1 Sunderland GT, Belch JJ, Sturrock RD, et al. A double-blind randomised placebo controlled trial of hexopal in primary Raynaud’s disease. Clin Rheumatol . 1988;7:46-49.
2 DiGiacomo RA, Kremer JM, Shah DM. Fish-oil dietary supplementation in patients with Raynaud’s phenomenon: a double-blind, controlled, prospective study. Am J Med . 1989;86:158-164.
3 Ringer TV, Hughes GS, Spillers CR, et al. Fish oil blunts the pain response to cold pressor testing in normal males [abstract]. J Am Coll Nutr . 1989;8:435.
4 Belch JJ, Shaw B, O’Dowd A, et al. Evening primrose oil (Efamol) as a treatment for cold-induced vasospasm (Raynaud’s phenomenon). Prog Lipid Res. 1986;25:335-340.
5 Belch JJ, Shaw B, O’Dowd A, et al. Evening primrose oil (Efamol) in the treatment of Raynaud’s phenomenon: a double-blind study. Thromb Haemost . 1985;54:490-494.
6 Jung F, Mrowietz C, Kiesewetter H, et al. Effect of Ginkgo biloba on fluidity of blood and peripheral microcirculation in volunteers. Arzneimittelforschung . 1990;40:589-593.
7 Khan F, Litchfield SJ, McLaren M, et al. Oral L-arginine supplementation and cutaneous vascular responses in patients with primary Raynaud's phenomenon. Arthritis Rheum . 1997;40:352-357.
8 Muir AH, Robb R, McLaren M, et al. The use of ginkgo biloba in Raynaud's disease: a double-blind placebo-controlled trial. Vasc Med . 2002;7:265-267.
9 Mavrikakis ME, Lekakis JP, Papamichael CM, et al. Ascorbic acid does not improve endothelium-dependent flow-mediated dilatation of the brachial artery in patients with Raynaud's phenomenon secondary to systemic sclerosis. Int J Vitam Nutr Res . 2003;73:3-7.
10 Raynaud's Treatment Study Investigators. Comparison of sustained-release nifedipine and temperature biofeedback for treatment of primary Raynaud’s phenomenon. Results from a randomized clinical trial with 1-year follow-up. Arch Intern Med . 2000;160:1101-1108.
11 Freedman RR, Ianni P, Wenig P. Behavioral treatment of Raynaud's phenomenon in scleroderma. J Behav Med . 1984;7:343-353.
12 Hahn M, Steins A, Mohrle M et al. Is there a vasospasmolytic effect of acupuncture in patients with secondary Raynaud phenomenon? J Dtsch Dermatol Ges . 2005;2:758-762.
- Reviewer: EBSCO CAM Review Board
- Review Date: 09/2014 -
- Update Date: 03/18/2015 -