|Blood Supply and Liver|
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Symptoms of excess copper in the liver include:
- Jaundice—yellowing of the skin and eyes
- Swollen abdomen
- Pain in the abdomen
- Vomiting blood
- Fluid buildup in the legs
- Symptoms of excess copper in the brain include:
- Symptoms of excess copper in the eyes include Kayser-Fleischer rings, which are rusty or brown-colored rings around the iris.
- Symptoms may also occur due to anemia, infections, poor blood clotting, kidney damage, or bone and joint disease from the extra copper
- Blood and urine tests
- Liver biopsy
- Remove the excess copper
- Prevent copper from building up again
- Improve all associated symptoms of copper overload
- Binding to the cooper. This helps release copper from organs into blood. Most of the copper will then be filtered in the kidneys and passed in the urine.
- Blocking the absorption of copper in the digestive tract.
- Avoid foods high in copper such as liver, shellfish, nuts, chocolate, and mushrooms.
- Have your drinking water checked for copper levels.
- Avoid multivitamins with copper.
American Association for the Study of Liver Diseases https://www.aasld.org
Wilson Disease Association http://www.wilsonsdisease.org
Canadian Liver Foundation http://www.liver.ca
Health Canada http://www.hc-sc.gc.ca
About Wilson Disease. Wilson Disease Association website. Available at: http://www.wilsonsdisease.org/about-wilsondisease.php. Accessed April 26, 2013.
Brewer GJ, Askari F, et al. Treatment of Wilson disease with ammonium tetrathiomolybdate: IV. Comparison of tetrathiomolybdate and trientine in a double-blind study of treatment of the neurologic presentation of Wilson disease. Arch Neurol. 2006 Apr;63(4):521-527.
Ferenci P. Wilson disease. Clin Gastroenterol Hepatol. 2005 Aug;3(8):726-733.
Wilson disease. EBSCO DynaMed website. Available at: https://dynamed.ebscohost.com/about/about-us. Updated April 8, 2013. Accessed February 27, 2014.
Wilson Disease. National Digestive Disease Information Clearinghouse website. Available at: http://digestive.niddk.nih.gov/ddiseases/pubs/wilson. Updated April 30, 2012. Accessed April 26, 2013.
- Reviewer: Michael Woods, MD
- Review Date: 02/2014 -
- Update Date: 02/27/2014 -